IB · HL/SL
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IB Biology Study Guide

Comprehensive coverage of the 2025 IB Biology syllabus across all four themes: Unity & Diversity, Form & Function, Interaction & Interdependence, and Continuity & Change: for both Higher Level and Standard Level students. Includes molecules, cells, gas exchange and transport, ecology, genetics, evolution, and HL-only extensions.

The Prep Den IB Biology study guide is your complete companion for revising the course: full topic-by-topic coverage, spaced-repetition flashcards, practice quizzes with worked explanations, a key-terms bank, and exam-technique tips. Use it as your main study guide or as a supplement to your textbook and class notes.

Topics Covered

Water, Cells & Diversity
Molecules & Membranes
Gas Exchange, Transport & Muscle (HL)
Adaptation & Ecological Niches
Metabolism & Body Systems
Genetics & Inheritance
Evolution & Climate Change
Exams, IA & Skills
HL extensions throughout

What you get

Full topic-by-topic curriculum coverage
Spaced-repetition flashcards for every topic
Multiple-choice quizzes with explanations
Term-matching vocabulary games
HL and SL content clearly labelled
Exam technique tips throughout
Key terms & definitions bank
12 months of access from purchase
Free Sample

A1: Water & Nucleic Acids

THE BIG PICTURE. Theme A opens with the molecular foundations of life: WATER (A1.1), the medium of all metabolism, and NUCLEIC ACIDS (A1.2), the molecules that store and transmit genetic information. Together they answer two questions that recur throughout IB Biology: what physical conditions are required for life? and how is biological information passed from generation to generation?

Sample Flashcards

Explain why water is a polar molecule and how this leads to hydrogen bonding.

Oxygen is more electronegative than hydrogen, causing unequal sharing of electrons in each O–H bond. This makes the oxygen end δ− and the hydrogen ends δ+. Hydrogen bonds form between the δ+ H of one molecule and a lone pair on the δ− O of an adjacent molecule.

State four biologically significant properties of water and give a biological example for each.

  1. Cohesion: water molecules stick together via H-bonds → continuous columns transported in xylem under tension.
  2. High specific heat capacity: resists temperature change → buffers aquatic habitats and the bodies of organisms (which are mostly water).

3.

Sample Key Terms

Hydrogen Bond

A weak electrostatic attraction between a δ+ hydrogen atom bonded to an electronegative atom (N, O, F) and a lone pair on another electronegative atom. In water: between adjacent molecules.

Cohesion

Attraction between water molecules due to hydrogen bonding. Creates surface tension and allows water to be pulled under tension in xylem vessels.

Adhesion

Attraction between water molecules and polar/charged surfaces. Enables capillary action in soil and plant cell walls.

What's Covered

  • A1: Water & Nucleic Acids
  • A2: Cell Origins & Structure
  • A3–A4: Diversity, Evolution & Conservation
  • B1: Carbohydrates, Lipids & Proteins
  • B2: Membranes, Organelles & Cell Specialisation
  • B3: Gas Exchange, Transport & Movement
  • B4: Adaptation & Ecological Niches
  • C1: Enzymes, Cell Respiration & Photosynthesis
  • C2–C3: Signalling & Body Systems
  • C4: Populations, Communities & Energy Transfer
  • D1: DNA Replication, Protein Synthesis & Mutations
  • D2–D3: Cell Division, Inheritance & Homeostasis
  • D4: Natural Selection, Stability & Climate Change
  • Exams, IA & Skills

14 topics · 171+ flashcards · quizzes & matching games included

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